Kate, this is a tricky one, and I can appreciate how you're feeling.
Paddy has a few health problems which, coupled with his age, over the past two years have led to his appetite being affected. He is often sick after a meal, and it's not unusual for him to lose weight quite rapidly over a few days when he goes off his food - sometimes he won't eat for almost three days at a time. Because he gets regular vet visits for his other health issues, we've been able to monitor him pretty well, and if things get too bad, he gets an appetite stimulant injection. However, because of Swampy's liver problems and the brain injury, it's hard to say whether this could just be an off day, or something more serious.
It's doubly awkward for you because your regular vet is away.
I think if you're able I would have a talk with the locum vet, explain Swampy's history and your concerns over the last couple of days. Emphasise the fact that you don't want to be traipsing Swampy to the surgery un-necessarily, particlarly having regard to the fits he had last time, and the stress he was under, physical and mental. A locum will generally be less willing to comment without sight of their patient, but he may have some ideas about whether you could safely leave a consultation a day or two, and see how Swampy progresses in the interim. Obviously you'd monitor him carefully yourself, as you have been doing.
At least he is still eating a little. And he's toddled about on his own again.
I think my gut instinct in your position would be to see how it goes today - if he's okay in himself in all other respects (having regard to his recent trauma) then I would probably not stress him out with a trip to the vet, and would try to hold out until Thursday's home visit.