Thanks everyone - had a bad couple of days with her, but a bit better today - she tries to use the tray, but misses at least once a day, so i am currently changing the newspaper under the tray more often than the actual litter!! She will happily poo in the tray, but misses with wee's, so I Can't decide if it is her knees or not. She has been a bit off her food, I am hoping she was just fed up of it, so have bought her some different flavours today - had her on adult last night and this morning, but she does gulp more on it, so bought some different senior flavours today. Seraquin arrived yesterday, and as long as I break it into about 3 pieces (they are quite big tabs), she will happily eat them and ask for more - she has to have 2 tabs a day at the moment. She has figured out how to get on the bed, so was on and off 4 times this morning (by which point I gave up and got up - had already got up once to feed them), and I did get her some new toys today as well.