If he has any white on his nose, or the fur is very thin, yes. Pebbles had pre-cancerous scabs on her nose, steroids did keep it at bay, but as MM says, it isn't very easy to treat on the nose, so prevention is much better.
MM, my pet one is in a pump applicator, i just put enough on my fingers before I go near the cat, so the noise doesn't bother them.